Developing a Novel Tool to Study the Transition from Acute to Chronic PainGrant Type: Young Investigator Grant, First Year
Institute: Institute for Drug Research, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem
Chronic pain is defined as a pain that persists beyond the usual healing period. Continuous or intermittent, it can consume all aspects of a person's life, making it a massive socioeconomic burden for the community. Here we propose to study how an acute pain, normally relieves over time, transforms into a chronic pain. We will use a unique natural pharmacological tool we recently identified to study the pain behavior in animals and the cellular changes underlying chronic pain development. This study will therefore enhance our understanding of how chronic pain is induced, and will facilitate the development of specific analgesics.